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How Endometriosis Affects Conception
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How Endometriosis Affects Conception by: Dr.
Mike Berkley
Endometriosis is a common, yet poorly
understood disease. It can strike women of any socioeconomic class,
age, or race. It is estimated that between 10 and 20 percent of
American women of childbearing age have endometriosis.
While
some women with endometriosis may have severe pelvic pain, others who
have the condition have no symptoms. Nothing about endometriosis is
simple, and there are no absolute cures. The disease can affect a
woman's whole existence-her ability to work, her ability to
reproduce, and her relationships with her mate, her child, and everyone
around her.
What is Endometriosis?
The name
endometriosis comes from the word "endometrium," the tissue that lines
the inside of the uterus. If a woman is not pregnant, this tissue
builds up and is shed each month. It is discharged as menstrual flow at
the end of each cycle. In endometriosis, tissue that looks and acts
like endometrial tissue is found outside the uterus, usually inside the
abdominal cavity. Endometrial tissue residing outside the uterus
responds to the menstrual cycle in a way that is similar to the way
endometrium usually responds in the uterus.
At the end of every
cycle, when hormones cause the uterus to shed its endometrial lining,
endometrial tissue growing outside the uterus will break apart and
bleed. However, unlike menstrual fluid from the uterus, which is
discharged from the body during menstruation, blood from the misplaced
uterus has no place to go. Tissues surrounding the area of
endometriosis may become inflamed or swollen. The inflammation may
produce scar tissue around the area of endometriosis. These endometrial
tissue sites may develop into what are called "lesions," "implants,"
"nodules," or "growths."
Endometriosis is most often found in
the ovaries, on the fallopian tubes, and the ligaments supporting the
uterus, in the internal area between the vagina and rectum, on the
outer surface of the uterus, and on the lining of the pelvic cavity.
Infrequently, endometrial growths are found on the intestines or in the
rectum, on the bladder, vagina cervix, and vulva (external genitals),
or in abdominal surgery scars, Very rarely, endometrial growths have
been found outside the abdomen, in the thigh, arm, or lung.
Physicians may use stages to describe the severity of
endometriosis. Endometrial implants that are small and not widespread
are considered minimal or mild endometriosis. Moderate endometriosis
means that larger implants or more extensive scar tissue is present.
Severe endometriosis is used to describe large implants and extensive
scar tissue.
What are the Symptoms?
Most commonly, the
symptoms of endometriosis start years after menstrual periods begin.
Over the years, the symptoms tend to gradually increase as the
endometriosis areas increase in size. After menopause, the abnormal
implants shrink away and the symptoms subside. The most common symptom
is pain, specially excessive menstrual cramps (dysmenorrhea) which may
be felt in the abdomen or lower back or pain during or after sexual
activity (dyspareunia). Infertility occurs in about 30-40 percent of
women with endometriosis.
Rarely, the irritation caused by
endometrial implants may progress into infection or abscesses causing
pain independent of the menstrual cycle.
Endometrial patches
may also be tender to touch or pressure, the intestinal pain may also
result from endometrial patches on the walls of the colon or intestine.
The amount of pain is not always related to the severity of the
disease. Some women with severe endometriosis have no pain; while
others with just a few small growths have incapacitating
pain.
Endometrial cancer is very rarely associated with
endometriosis, occurring in less than 1 percent of women who have the
disease. When it does occur, it is usually found in more advanced
patches of endometriosis in older women and the long-term outlook in
these unusual cases is reasonably good.
How is Endometriosis
Related to Fertility Problems?
Severe endometriosis with
extensive scarring and organ damage may affect fertility. It is
considered one of the three major causes of female infertility.
However, unsuspected or mild endometriosis is a common finding
among infertile women. How this type of endometriosis affects fertility
is still not clear.
While the pregnancy rates for patients with
endometriosis remain lower than those of the general population, most
patients with endometriosis do not experience fertility problems. We do
not have a clear understanding of the cause-effect relationship of
endometriosis and infertility
What is the Cause of
Endometriosis?
The cause of endometriosis is still unknown. One
theory is that during menstruation some of the menstrual tissue backs
up through the fallopian tubes into the abdomen, where it implants and
grows. Another theory suggests that endometriosis may be a genetic
process or that certain families may have predisposing factors to
endometriosis. In the latter view, endometriosis is seen as the tissue
development process gone awry.
According to the theory of
traditional chinese medicine, endometriosis is a disease which is
caused by the stagnation of blood. Blood stagnation may occur due to
one or more abortions or lower abdominal or pelvic surgeries.
Additionally, engaging in sexual intercourse during
menstruation may very likely over time cause blood stagnation.
Emotional trauma, severe stress, physical or emotional abuse can all
lead to the stagnation of blood.
Additionally, diet may be a
precipitating factor. The constant, long term ingestion of cold foods
can congeal blood and thus contribute to the stagnation thereof. Cold
foods include raw vegetable, ices, ice cream, ice in drinks, frozen
yogurt, etc. Remember, cold congeals. Think about what happens to a
normal glass of water when put in the freezer. It turns to ice.
The blood is affected similarly. That is to say, it congeals,
doesn't flow smoothly and can form endometrial adhesions, chocolate
cysts, uterine fibroids. Whatever the cause of endometriosis, its
progression is influenced by various stimulating factors such as
hormones or growth factors. In this regard, investigators are studying
the role of the immune system in activating cells that may secrete
factors which, in turn, stimulate endometriosis.
In addition to
these new hypotheses, investigators are continuing to look into
previous theories that endometriosis is a disease influenced by
delaying childbearing. Since the hormones made by the placenta during
pregnancy prevent ovulation, the progress of endometriosis is slowed or
stopped during pregnancy and the total number of lifetime cycles is
reduced for a woman who had multiple pregnancies.
How is
Endometriosis Diagnosed?
Diagnosis of endometriosis begins with
a gynecologist evaluating the patient's medical history. A complete
physical exam, including a pelvic examination, is also necessary.
However, diagnosis of endometriosis is only complete when proven by a
laparoscopy, a minor surgical procedure in which a laparoscope (a tube
with a light in it) is inserted into a small incision in the abdomen.
The laparoscope is moved around the abdomen, which has been
distended with carbon dioxide gas to make the organs easier to see. The
surgeon can then check the condition of the abdominal organs and see
the endometrial implants. The laparoscopy will show the locations,
extent, and size of the growths and will help the patient and her
doctor make better-informed decisions about treatment. Endometriosis is
a long-standing disease that often develops slowly.
What is the
Treatment?
While the treatment for endometriosis has varied
over the years, doctors now agree that if the symptoms are mild, no
further treatment other than medication for pain may be needed.
Endometriosis is a progressive disorder.
It is my opinion that
by not treating endometriosis it will get worse. Treatment should
immediately after a positive diagnosis is made. The pain associated
with endometriosis can be diminished by using acupuncture and herbal
medicine. I have treated many women with endometriosis and have
successfully alleviated pain and slowed down growth and recurrence of
endometriosis.
For those patients with mild or minimal
endometriosis who wish to become pregnant, doctors are advising that,
depending on the age of the patient and the amount of pain associated
with the disease, the best course of action is to have a trial period
of unprotected intercourse for 6 months to 1 year. If pregnancy does
not occur within that time, then further treatment may be needed.
Again, these patients should consider herbal medicine to aid in the
process of conception.
About The
Author
Dr. Mike Berkley is the founder and director
of The Berkley Center for Reproductive Wellness, in New York. He works
exclusively in the area of reproductive medicine and enjoys working in
conjunction with some of New York’s most prestigious reproductive
endocrinologists. Sign up for his free newsletter at www.BerkleyCenter.com.
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